Tuesday, March 9, 2010

The Problems of Medical Thought

Watched a PBS documentary on DNA and Curing Cancer. Really fascinating and informative. So if I've walked away from it correctly... If I had to sum up in a few lines the current endeavors of the medical genetic field it would be as follows:

With the Genome mapped and many if not all markers of various "cancerous" genes/amino acids?? (don't really know the correct terms) identified we plan to develop drugs that hone in and target those parts of the gene outputting the corrupted instructions, shut them down, and thereby allow the DNA to resume it's functions as it should. The first paradigm of that being Gleevec.

Now before I give my 2 cents of critique I'd like to request the granting of one assumption for the purposes of this argument. That assumption being that God is dead i.e. no God/atheism. This way there shouldn't be any confusing my logic for religion.

Now, as an atheist (for the course of this post) let me express my concerns with the current Medical approach/attitude. Namely, that it gives no thought or concern to the higher sources of causation that caused the cancer genes to go bad in the first place. It assumes that the point of corruption in the gene code is like the first point of origin in time with no history or causations before it.

It fails to ask the begging questions as to why and how do the genes go corrupt in the first place (other than to attribute everything to randomness of events). And so you may think you're solving the problem but in actuality what you're doing is cutting off a venue for the "real problem" to express itself or manifest.

A metaphor: When I worked in the cafeteria giving out servings everyone wanted an extra portion of chicken beyond their allotment per their ticket. Now, what would happen if I obliged to all of them and gave them? Sure initially everyone is happy with their extra portions but in the end the catering service has to shut down because they go broke.

In other words, when dealing with any complex system, you can't "hijack" the system from within a particular middle stage in the process and think there will be no reprecussions of your actions on more macro/higher levels.

So here you plan on hijacking the gene. Shutting down it's "bad output" and forcing it to output what you want... but until you know what was the cause for the corruption in the first place how do you know you're not just creating bigger problems on higher more broader levels? How do you know that the corrupt output wasn't needed for manifesting a different more fundamental problem that now must find a different way for expression? How do you know that the "bad gene instructions" are really bad?

My problem is not at all with the further studying of our genes, nor with the administering of current treatments that do seem to cure the patients with no visible side effects. Wonderful.

My problem is with the attitude of it all; in thinking that this is the end-all; that you can ignore any deeper levels of causality and think you can hold this particular level of reality hostage and have it meet all of your demands as you wish them.

If we must take this path so be it, but let it be done with trepidation and respect, not brash aarogance and exploitation.

It essentially becomes the same issue as the hiding of the Sefer Refuot by Chizkiyahu or the engaging in קבלה מעשית through השבעת שמות למלאכים.

Monday, March 8, 2010

Just Notes -- רעיא מהימנא פר' משפטים

עי' רעיא מהימנא משפטים קיד וכל הענין

1- כי ינצו אנשים אלו מיכאל וס"מ וכו' -- קשיא לי טובא ליישב המשך הפסוקים לפי זה דאיך נפרש "ואם יהיה אסון"?? ח"ו להגיד אפשרות אסון על כנסת ישראל... וגם קשיא לי ונגפו דמשמע שניהם גורמים....

2- פקודא בתר דא להשיב אבידה ואבתריה להשיב הגזל וכו' בההוא זמנא יתקיימו בך תרין פקודין חד הקם תקים תניינא עזוב תעזוב וכו' לכאורה צ"ל דאין כוונת ר"ש לפרש הפסוקים ממש על משה רבינו דא"כ איך ניישב הפסוקים של השבת אבידה ופריקה שמדברים דוקא בשור אויבך ושונאך??

3- השווה: עזב תעזב עמו... הקם תקים עמו... ויקח משה את עצמות יוסף עמו

4- Look at how many times the 3rd person possesive is used throughout Pr' Mishpatim! Mind Boggling! From the beginnning of the Parasha until ששי I count 74 times 3rd person possessive is used and many of the pesukim end with the "Vav Cholem" ending e.g. ודל לא תהדר בריבו... עזוב תעזוב עמו... ויצאה אשתו עמו... etc. Very appropriate then with all the וא"ו endings that the parasha should make up the ספר הברית (Shemot 24:7).

5- עמו" והשורש "עם" מופיעים גם הרבה פעמים בפר' משפטים".....




Saturday, February 27, 2010

Molecular Biology- DNA Fork & Replication

Just was looking into the subject on account of a BioMed stock I purchased. Was watching a video on YouTube regarding DNA Replication

So there's a part where they explain that the double helix of the DNA strand gets forked into two separate strands.

One strand gets smoothly "copied" just as soon as it's spooling out of the fork location. Continuously in one direction.

The other strand (because of it's directionality) needs to be taken section by section at a time and is copied backwards.

Compare all of that with ויסע ויבא ויט (Shemot 14) and it's pretty striking.

יום הששי ויכולו השמים

יום הששי ויכולו השמים

Besides for the most obvious of questions as to the splitting of the שם הויה in half between the sixth and seventh day I find it more than interesting upon examining the second half of ויכולו השמים

the "male" vav (ו) placed with the "female" כלה and the "female" heh (ה) placed with the "male" שמים. Never noticed that before....

Tuesday, January 19, 2010

...and one post to bind them...

This new peirush on the Zohar מתוק מדבש by Daneil Frish is just amazing!! I must have read this Zohar in the beginning of Parshat Trumah 3 or 4 separate times and never did I have the clarity that I got from reading it with the מתוק מדבש! To me this does for Zohar what Rashi did for Gemara.

Anyway, things have already become too complex to type all the interconnections out so all I want to do is just annotate it all. See the מתוק מדבש on the Zohar 127a on the sugya of אפריון ואפרסמון , then... compare with the following posts:




Sunday, January 10, 2010

Phone Call

The gematria of the hebrew suffix פון being equal to that of קול, both rendering 136. Hence the term Phone (Fon) Call (Kol).

Came to me when calculating the value of סנדלפו"ן . Interestingly enough the name can be broken into two parts, 136 + 144, or קדם + קול , together yielding 280, פר, and מנצפ"ך.

Not that I know what to make of it of course...

Additionaly, this i found from Hebrew Wikipedia regarding the name:

פירוש השם

החוקר מאיר בר-אילן טוען‏‏[1] כי השם סנדלפון מורכב משני בסיסים ביוונית: "סון" (=אחד ) ו-"(א)דלפון" (=אח), כלומר: 'מי שאינו נשלח לבדו'. פירוש זה עולה בקנה אחד עם האמונה כי סנדלפון הוא אחיו של מטטרון.

בספר הזוהר ('רעיא מהימנא') מוסבר שמו כרמז להיותו כמו הנעל והסנדל לכבוד השכינה, כלומר למרות עצמתו וגודלו העצום הוא רק הסנדל של כבוד האל.

פירוש אחר הוא לפי פירוק השם להברות: 'סנ-דל-פון' ותרגומן "שנואי דל פונה", כלומר המלאך פונה לתפילותם של ישראל גם כשהם דלים ממצוות ושנואים על ידי אומות העולם.

Friday, January 1, 2010

Random Fact - Horse and Donkey Chromosomes

Find it intriguing although have no idea what to do with it. Read it in Wikipedia.

Horses have 64 chromosomes. Donkeys have 62. When they mate a mule has 63 chromosomes and hence cannot reproduce.

וצע"ע